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Gut Health Impacts Our Entire Body

We have always associated our gut with a digestion function. However, we now have enough evidence to say that our gut has an impact on health far beyond digestion.1

70% of immune cells are located in your gut

From the day we are born, our gut microbiome trains and regulates our immune system, making it crucial for our overall health and wellbeing.

Plants and fiber-rich food leads to rich diversity of gut microbiome and strong immunity

For over 200,000 years we were hunter-gatherers

We used to consume mostly plant-based and fiber-rich diet. This diet supported a rich diversity of bacteria in our gut. Our body evolved to co-exist with these bacteria and developed an interdependent relationship.

Modern nutrient-poor processed foods combined with antibiotics and increased sanitation lead to poor diversity of gut microbiome and weak immunity

Modern diets have changed our gut microbiome

Today our lifestyle is packed with calorie-rich, nutrient-poor processed foods. Coupled with an increased use of antibiotics and sanitation, this has changed our gut microbiome.

"Aspects of our microbial identity have gone extinct and this extinction results in a mismatch between our recently adapted microbiota and our more slowly adapting human genome."3
Dr. Erica D. Sonnenburg and Prof. Justin L. Sonnenburg
Department of Microbiology and Immunology, Stanford University School of Medicine

Chronic conditions are going UP

In fact, 2 out of 3 people in the UK are affected by the conditions caused by a dysregulated immune system and chronic inflammation.
ALERGIES4

20M affected
1 in 3 at risk

DIABETES5

5M affected
14M at risk

CANCER6

3M affected
1 in 2 at risk

ASTHMA7

5.4M affected

CARDIOVASCULAR DISEASES8

7.6M affected
24% of all deaths

"Fermented food intake increases microbiota diversity and decreases inflammation markers"9
Hannah C. Wastyk et al.
Cell |  Volume 184, Issue 16, P4137-4153, 2021

References

  1. Singh, R.K., Chang, HW., Yan, D. et al. Influence of diet on the gut microbiome and implications for human health. J Transl Med 15, 73 (2017). https://doi.org/10.1186/s12967-017-1175-y
  2. Wiertsema, S.P., van Bergenhenegouwen, J., Garssen, J., Knippels, L.M.J. The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies. Nutrients 88, (2021). https://doi.org/10.3390/nu13030886
  3. Sonnenburg, E.D., Sonnenburg, J.L. The ancestral and industrialized gut microbiota and implications for human health. Nat Rev Microbiol 17, 383–390 (2019). https://doi.org/10.1038/s41579-019-0191-8.
  4. Allergy UK, https://www.allergyuk.org/about-allergy/statistics-and-figures. Accessed in December 2022.
  5. Diabetes UK. https://www.diabetes.org.uk/about-us/about-the-charity/our-strategy/statistics. Accessed in November 2024.
  6. Macmillan Cancer Support. https://www.macmillan.org.uk/about-us/what-we-do/research/cancer-prevalence. Accessed in December 2022.
  7. Asthma and Lung UK. https://www.asthma.org.uk/support-us/campaigns/publications/difficult-and-severe-asthma-report/. Accessed in December 2022.
  8. British Heart Foundation. https://www.bhf.org.uk/what-we-do/our-research/heart-statistics. Accessed in December 2022.
  9. Wastyk, H. C., Fragiadakis, G. K., Perelman, D., et al. Gut-microbiota-targeted diets modulate human immune status. Cell 184(16), 4137-4153 (2021). https://doi.org/10.1016/j.cell.2021.06.019.
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